Investigation of The Cellular Response to Bone Fractures: Evidence for Flexoelectricity.
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ABSTRACT:
SUBMITTER: Nunez-Toldra R
PROVIDER: S-EPMC6959267 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Publications
Investigation of The Cellular Response to Bone Fractures: Evidence for Flexoelectricity.
Núñez-Toldrà Raquel R Vasquez-Sancho Fabian F Barroca Nathalie N Catalan Gustau G
Scientific reports 20200114 1
The recent discovery of bone flexoelectricity (strain-gradient-induced electrical polarization) suggests that flexoelectricity could have physiological effects in bones, and specifically near bone fractures, where flexoelectricity is theoretically highest. Here, we report a cytological study of the interaction between crack stress and bone cells. We have cultured MC3T3-E1 mouse osteoblastic cells in biomimetic microcracked hydroxyapatite substrates, differentiated into osteocytes and applied a s ...[more]
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