Compartmentalized profiling of amniotic fluid cytokines in women with preterm labor.

ABSTRACT:

Objective

Amniotic fluid cytokines have been implicated in the mechanisms of preterm labor and birth. Cytokines can be packaged within or on the surface of extracellular vesicles. The main aim of this study was to test whether the protein abundance internal to and on the surface of extracellular vesicles changes in the presence of sterile intra-amniotic inflammation and proven intra-amniotic infection in women with preterm labor as compared to the women with preterm labor without either intra-amniotic inflammation or proven intra-amniotic infection.

Study design

Women who had an episode of preterm labor and underwent an amniocentesis for the diagnosis of intra-amniotic infection or intra-amniotic inflammation were classified into three groups: 1) preterm labor without either

SUBMITTER: Bhatti G 

PROVIDER: S-EPMC6964819 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature