Comparative analysis of 2-year outcomes in GRIT and TRUFFLE trials.

ABSTRACT:

Objective

To explore the effect on perinatal outcome of different fetal monitoring strategies for early-onset fetal growth restriction (FGR).

Methods

This was a cohort analysis of individual participant data from two European multicenter trials of fetal monitoring methods for FGR: the Growth Restriction Intervention Study (GRIT) and the Trial of Umbilical and Fetal Flow in Europe (TRUFFLE). All women from GRIT (n = 238) and TRUFFLE (n = 503) who were randomized between 26 and 32 weeks' gestation were included. The women were grouped according to intervention and monitoring method: immediate delivery (GRIT) or delayed delivery with monitoring by conventional cardiotocography (CTG) (GRIT), computerized CTG (cCTG) only (GRIT and TRUFFLE) or cCTG and ductus venosus (DV) Doppler

SUBMITTER: Ganzevoort W 

PROVIDER: S-EPMC6973288 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature