Lipidomic profiles, lipid trajectories and clinical biomarkers in female elite endurance athletes.

ABSTRACT: We assessed whether blood lipid metabolites and their changes associate with various cardiometabolic, endocrine, bone- and energy-related comorbidities of Relative Energy Deficiency in Sport (RED-S) in female elite endurance athletes. Thirty-eight Scandinavian female elite athletes underwent a day-long exercise test. Five blood samples were obtained during the day - at fasting state and before and after two standardized exercise tests. Clinical biomarkers were assessed at fasting state, while untargeted lipidomics was undertaken using all blood samples. Linear and logistic regression was used to assess associations between lipidomic features and clinical biomarkers. Overrepresentations of findings with P < 0.05 from these association tests were assessed using Fisher's exact tests. Self-org

SUBMITTER: Varga TV 

PROVIDER: S-EPMC7012926 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature