Is haemoglobin below 7.0 g/dL an optimal trigger for allogenic red blood cell transfusion in patients admitted to intensive care units? A meta-analysis and systematic review.

ABSTRACT:

Objectives

We employed a comprehensive systematic review and meta-analysis to assess benefits and risks of a threshold of haemoglobin level below 7 g/dL versus liberal transfusion strategy among critically ill patients, and even patients with septic shock.

Design

Systematic review and meta-analysis.

Data sources

We performed systematical searches for relevant randomised controlled trials (RCTs) in the Cochrane Library, EMBASE and PubMed databases up to 1 September 2019.

Eligibility criteria

RCTs among adult intensive care unit (ICU) patients comparing 7 g/dL as restrictive strategy with liberal transfusion were incorporated.

Data extraction and synthesis

The clinical outcomes, including short-term mortality, length of hospital stay, length of ICU stay, m

SUBMITTER: Yao RQ 

PROVIDER: S-EPMC7045194 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature