Project description:Substituted triphenylenes show promise as organic semiconductors because of their ability to form columnar liquid crystalline phases featuring extended π-stacked arrays. While there are several methods for preparing triphenylenes, including oxidative cyclization reactions such as the Scholl reaction, as well as transition metal-catalyzed aryne cyclotrimerization, these methods are not effective for electron deficient triphenylenes. Here we demonstrate that the nickel-mediated Yamamoto coupling of o-dibromoarenes is a concise and efficient way to prepare substituted triphenylenes, including electron-deficient systems that are otherwise challenging to prepare. We also demonstrate the application of this approach to prepare electron deficient discotic mesogens composed of triphenylenes bearing imide and thioimide groups.
Project description:Conjugated microporous polymers (CMPs) have conjugated skeleton and permanent porosity, and exhibit huge potential in developing novel functional materials for resolving the challenging energy and environment issues. Metal-containing CMPs often exhibited unique properties. In the present manuscript, ferrocene-based conjugated microporous polymers (FcCMPs) were designed and synthesized with 1,1'-dibromoferrocene and 5,10,15,20-Tetrakis(4- bromophenyl) porphyrin (FcCMP-1) or Tetra (p-bromophenyl) methane (FcCMP-2) as building units via Yamamoto coupling. FcCMPs were amorphous, and exhibited excellent thermal and physicochemical stability. The BET surface area of FcCMP-1 and FcCMP-2 was 638 m2/g and 422 m2/g, respectively. In comparison with FcCMP-2, FcCMP-1 displayed better gas storage capacity due to higher porosity. FcCMPs were also used as an adsorbent for removal of methyl violet from aqueous solution, and exhibited excellent adsorption properties due to the interaction between electron-rich conjugated structure of the polymers and methyl violet with cationic groups. Moreover, FcCMPs could be extracted and regenerated by an eluent and then re-used for high efficient removal of methyl violet.
Project description:This research investigates the effects of electricity consumption (major independent variable), per capita income, real exchange rate, import and export on manufacturing output by using yearly time series data for the period of 1980-2016 with regard to 10 late industrialized nations. The ARDL bound testing approach, the way to deal with cointegration is applied to estimate the long-run connection between the variables. While, error correction method (ECM) is used to find the short-run dynamics. To test the causality among the variables, Toda-Yamamoto test is performed. The results demonstrate the existence of short-run and long-run relationship among the variables and Toda-Yamamoto causality results support the existence of growth, conservation, feedback and neutrality hypotheses for different nations. The difference in the results can be attributed to structural and macroeconomic parameters. In general, this research brings out a fresh lead of knowledge for late industrialized nations to strengthen their economic development through proficient utilization of energy consumption.
Project description:The specific growth rate of the perioperative carbohydrate antigen 19‐9 values was not related to the prognosis of extrahepatic cholangiocarcinoma.
Project description:Cell cycle and nuclear state imaging readouts for PC3 cells treated with ligand and ECMp combinations to explore the role of microenvironmental signals in cancer growth.
Project description:HMEC240L cells were grown in standard 8 well MEMA for 72h and then fixed using 2% paraformaldehyde. Cells were stained with DAPI (nuclei), KRT5(basal lineage), KRT19(luminal lineage) and EdU(Active S phase). The cells were imaged on a Nikon HCA microscopy system, segmented with Cell Profiler, normalized using RUV and lowess using the spatial residuals as controls, and analyzed to identify microenvironment conditions that altered phenotypes of interest.