Increased circulating cytokine levels in African American women with obesity and elevated HbA1c.

ABSTRACT:

Purpose

Obesity has emerged as one of the biggest health crisis and is the leading cause of death and disabilities around the world. BMI trends suggest that majority of the increase in T2D is resulting from the increased prevalence of obesity. In fact, 85.2% of people with T2D are overweight or obese. The highest prevalence for obesity is seen in non-Hispanic, African American women (56.6%). T2D is classified as an inflammatory disease because of elevated, circulating pro-inflammatory cytokines and acute-phase inflammatory proteins. This study was designed to determine how high HbA1c and serum glucose correlate with circulatory cytokine levels in obese, African American women.

Methods

We investigated cytokine/chemokine serum levels using a multiplex assay. Then we used Pairw

SUBMITTER: Williams A 

PROVIDER: S-EPMC7058975 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature