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Metabolic syndrome in indigenous communities in Mexico: a descriptive and cross-sectional study.

ABSTRACT: BACKGROUND:An Amerindian genetic background could play an important role in susceptibility to metabolic diseases, which have alarmingly increased in recent decades. Mexico has one of the highest prevalences of metabolic disease worldwide. The purpose of this study was to determine the prevalence of metabolic syndrome and its components in a population with high Amerindian ancestry. METHODS:We performed a descriptive, quantitative, and analytical cross-sectional study of 2596 adult indigenous volunteers from 60 different ethnic groups. Metabolic syndrome and its components were evaluated using the American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement criteria. RESULTS:The overall prevalence of metabolic syndrome in the indigenous Mexican population was 50.3%. Although females had a higher prevalence than males (55.6% vs. 38.2%), the males presented with combinations of metabolic syndrome components that confer a higher risk of cardiovascular disease. The most frequent metabolic syndrome component in both genders was low HDL-cholesterol levels (75.8%). Central obesity was the second most frequent component in females (61%), though it had a low prevalence in males (16.5%). The overall prevalence of elevated blood pressure was 42.7% and was higher in males than females (48.8 vs. 40%). We found no gender differences in the overall prevalence of elevated triglycerides (56.7%) or fasting glucose (27.9%). CONCLUSIONS:We documented that individuals with Amerindian ancestry have a high prevalence of metabolic syndrome. Health policies are needed to control the development of metabolic disorders in a population with high genetic risk.

SUBMITTER: Mendoza-Caamal EC

PROVIDER: S-EPMC7076922 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

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Metabolic syndrome in indigenous communities in Mexico: a descriptive and cross-sectional study.

Mendoza-Caamal Elvia Cristina EC Barajas-Olmos Francisco F García-Ortiz Humberto H Cicerón-Arellano Isabel I Martínez-Hernández Angélica A Córdova Emilio J EJ Esparza-Aguilar Marcelino M Contreras-Cubas Cecilia C Centeno-Cruz Federico F Cid-Soto Miguel M Morales-Marín Mirna Edith ME Reséndiz-Rodríguez Adriana A Jiménez-Ruiz Juan Luis JL Salas-Martínez María Guadalupe MG Saldaña-Alvarez Yolanda Y Mirzaeicheshmeh Elaheh E Rojas-Martínez María Rosalba MR Orozco Lorena L

BMC public health 20200317 1

<h4>Background</h4>An Amerindian genetic background could play an important role in susceptibility to metabolic diseases, which have alarmingly increased in recent decades. Mexico has one of the highest prevalences of metabolic disease worldwide. The purpose of this study was to determine the prevalence of metabolic syndrome and its components in a population with high Amerindian ancestry.<h4>Methods</h4>We performed a descriptive, quantitative, and analytical cross-sectional study of 2596 adult ...[more]

PMID: 32183766

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Dataset Information

Metabolic syndrome in indigenous communities in Mexico: a descriptive and cross-sectional study.

Publications

Metabolic syndrome in indigenous communities in Mexico: a descriptive and cross-sectional study.

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