Massively parallel microwire arrays integrated with CMOS chips for neural recording.

ABSTRACT: Multi-channel electrical recordings of neural activity in the brain is an increasingly powerful method revealing new aspects of neural communication, computation, and prosthetics. However, while planar silicon-based CMOS devices in conventional electronics scale rapidly, neural interface devices have not kept pace. Here, we present a new strategy to interface silicon-based chips with three-dimensional microwire arrays, providing the link between rapidly-developing electronics and high density neural interfaces. The system consists of a bundle of microwires mated to large-scale microelectrode arrays, such as camera chips. This system has excellent recording performance, demonstrated via single unit and local-field potential recordings in isolated retina and in the motor cortex or striatum o

SUBMITTER: Obaid A 

PROVIDER: S-EPMC7083623 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature