Ontology highlight
ABSTRACT:
SUBMITTER: Rocha B
PROVIDER: S-EPMC7124476 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Rocha Beatriz B Cillero-Pastor Berta B Eijkel Gert G Calamia Valentina V Fernandez-Puente Patricia P Paine Martin R L MRL Ruiz-Romero Cristina C Heeren Ron M A RMA Blanco Francisco J FJ
Molecular & cellular proteomics : MCP 20200124 4
In osteoarthritis (OA), impairment of cartilage regeneration can be related to a defective chondrogenic differentiation of mesenchymal stromal cells (MSCs). Therefore, understanding the proteomic- and metabolomic-associated molecular events during the chondrogenesis of MSCs could provide alternative targets for therapeutic intervention. Here, a SILAC-based proteomic analysis identified 43 proteins related with metabolic pathways whose abundance was significantly altered during the chondrogenesis ...[more]