Antipsychotics and the Risk of Mortality or Cardiopulmonary Arrest in Hospitalized Adults.

ABSTRACT:

Objectives

Prior studies in outpatient and long-term care settings demonstrated increased risk for sudden death with typical and atypical antipsychotics. To date, no studies have investigated this association in a general hospitalized population. We sought to evaluate the risk of death or nonfatal cardiopulmonary arrest in hospitalized adults exposed to antipsychotics.

Design

Retrospective cohort study.

Setting

Large academic medical center in Boston, Massachusetts.

Participants

All hospitalizations between 2010 and 2016 were eligible for inclusion. We excluded those admitted directly to the intensive care unit (ICU), obstetric and gynecologic or psychiatric services, or with a diagnosis of a psychotic disorder.

Intervention

Typical and atypical antipsyc

SUBMITTER: Basciotta M 

PROVIDER: S-EPMC7155937 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature