Photoelectrocyclization Reactions of Amidonaphthoquinones.

ABSTRACT: Readily available acrylamide naphthoquinones can be converted into the corresponding aza-anthraquinones using 6π-photoelectrocyclization reactions. Not only do these reactions not proceed thermally but, as demonstrated here, they can also be used to generate a range of aza-anthraquinone and aza-tetracycline derivatives including the natural products griffithazanone A and marcanine A. Several of the aza-anthraquinones generated in this work showed antibacterial activity.

SUBMITTER: Yin J 

PROVIDER: S-EPMC7164668 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature