Clinical impact of rapid molecular detection of respiratory pathogens in patients with acute respiratory infection.

ABSTRACT:

Background

Acute respiratory infections (ARI) are a leading cause of morbidity and mortality worldwide. There is a need to demonstrate the clinical impact of using the new, rapid and sensitive molecular assays in prospectively designed studies.

Objectives

To study the impact on medical management of a rapid molecular assay in patients with respiratory infections.

Study design

A prospective, randomized, non-blinded study was performed in patients presenting to the Emergency Department during two respiratory seasons (2016-2017). Diagnosis was performed by FilmArray Respiratory Panel (FilmArray-RP) or by immunofluorescence assay (IFA).

Results

A total of 432 patients (156 children and 276 adults) were analyzed. Diagnosis with FilmArray-RP was associated with signi

SUBMITTER: Echavarria M 

PROVIDER: S-EPMC7172208 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature