A New Mechanism of Metal-Ligand Cooperative Catalysis in Transfer Hydrogenation of Ketones.

ABSTRACT: We report iridium catalysts IrCl(η⁵-Cp*)(κ²-(2-pyridyl)CH₂NSO₂C₆H₄X) (1-Me, X = CH₃ and 1-F, X = F) for transfer hydrogenation of ketones with 2-propanol that operate by a previously unseen metal-ligand cooperative mechanism. Under the reaction conditions, complexes 1 (1-Me and 1-F) derivatize to a series of catalytic intermediates: Ir(η⁵-Cp*)(κ²-(C₅H₄N)CHNSO₂Ar) (2), IrH(η⁵Cp*)(κ²-(2-pyridyl)CH₂NSO₂Ar) (3), and Ir(η⁵-Cp*)(κ³-(2-pyridyl)CH₂NSO₂Ar) (4). The structures of 1-Me and 4-Me were established by s

SUBMITTER: Demianets I 

PROVIDER: S-EPMC7224354 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature