Indocyanine green matching phantom for fluorescence-guided surgery imaging system characterization and performance assessment.

ABSTRACT:

Significance

Expanded use of fluorescence-guided surgery with devices approved for use with indocyanine green (ICG) has led to a range of commercial systems available. There is a compelling need to be able to independently characterize system performance and allow for cross-system comparisons.

Aim

The goal of this work is to expand on previous proposed fluorescence imaging standard designs to develop a long-term stable phantom that spectrally matches ICG characteristics and utilizes 3D printing technology for incorporating tissue-equivalent materials.

Approach

A batch of test targets was created to assess ICG concentration sensitivity in the 0.3- to 1000-nM range, tissue-equivalent depth sensitivity down to 6 mm, and spatial resolution with a USAF test chart. Comparis

SUBMITTER: Ruiz AJ 

PROVIDER: S-EPMC7240319 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature