Association between organ damage and mortality in systemic lupus erythematosus: a systematic review and meta-analysis.

ABSTRACT:

Objective

At least half of patients with systemic lupus erythematosus (SLE) develop organ damage as a consequence of autoimmune disease or long-term therapeutic steroid use. This study synthesised evidence on the association between organ damage and mortality in patients with SLE.

Design

Systematic review and meta-analysis.

Methods

Electronic searches were performed in PubMed, Embase, Cochrane Library and Latin American and Caribbean Health Sciences Literature for observational (cohort, case-control and cross-sectional) studies published between January 2000 and February 2017. Included studies reported HRs or ORs on the association between organ damage (measured by the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SD

SUBMITTER: Murimi-Worstell IB 

PROVIDER: S-EPMC7247371 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature