Dabigatran initiation in patients with non-valvular AF and first acute ischaemic stroke: a retrospective observational study from the SITS registry.

ABSTRACT:

Background and objective

The optimal timing for initiation of dabigatran after acute ischaemic stroke (AIS) is not established. We aimed to evaluate initiation timing and clinical outcomes of dabigatran in AIS patients with non-valvular atrial fibrillation (NVAF).

Design

Retrospective study based on prospectively collected data in SITS (Safe Implementation of Treatment in Stroke) Thrombolysis and Thrombectomy Registry from July 2014 to July 2018.

Participants

European NVAF patients (≥18 years) hospitalised after first-ever ischaemic stroke.

Setting

A multinational, observational monitoring register.

Intervention

Dabigatran initiation within 3 months after the ischaemic stroke.

Primary and secondary outcomes

The primary outcome was time from first-

SUBMITTER: Escudero-Martinez I 

PROVIDER: S-EPMC7247395 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature