Ontology highlight
ABSTRACT:
SUBMITTER: Jeudy S
PROVIDER: S-EPMC7253447 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Nature communications 20200527 1
DNA methylation is an important epigenetic mark that contributes to various regulations in all domains of life. Giant viruses are widespread dsDNA viruses with gene contents overlapping the cellular world that also encode DNA methyltransferases. Yet, virtually nothing is known about the methylation of their DNA. Here, we use single-molecule real-time sequencing to study the complete methylome of a large spectrum of giant viruses. We show that DNA methylation is widespread, affecting 2/3 of the t ...[more]