Comparison of intravitreal dexamethasone implant and anti-VEGF drugs in the treatment of retinal vein occlusion-induced oedema: a meta-analysis and systematic review.

ABSTRACT:

Objective

To compare the efficacy and safety of intravitreal dexamethasone (DEX) implant and anti-vascular endothelial growth factor (anti-VEGF) agents in the treatment of macular oedema secondary to retinal vein occlusion (RVO).

Design

Systematic review and meta-analysis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE).

Data sources

PubMed, Cochrane Library and ClinicalTrials.gov registry were searched from inception to 10 December 2019, without language restrictions.

Eligibility criteria

Randomised controlled trials (RCTs) and real-world observation studies comparing the efficacy of DEX implant and anti-VEGF agents for the treatment of patients with RVO, naïve or almost naïve to both arms, were included.

Data extrac

SUBMITTER: Ming S 

PROVIDER: S-EPMC7322510 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature