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Multicenter Ozone Study in oldEr Subjects (MOSES): Part 2. Effects of Personal and Ambient Concentrations of Ozone and Other Pollutants on Cardiovascular and Pulmonary Function.


ABSTRACT:

SUBMITTER: Rich DQ 

PROVIDER: S-EPMC7325421 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

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Multicenter Ozone Study in oldEr Subjects (MOSES): Part 2. Effects of Personal and Ambient Concentrations of Ozone and Other Pollutants on Cardiovascular and Pulmonary Function.

Rich D Q DQ   Frampton M W MW   Balmes J R JR   Bromberg P A PA   Arjomandi M M   Hazucha M J MJ   Thurston S W SW   Alexis N E NE   Ganz P P   Zareba W W   Koutrakis P P   Thevenet-Morrison K K  

Research report (Health Effects Institute) 20200301 192, Pt 2


<h4>Introduction</h4>The Multicenter Ozone Study of oldEr Subjects (MOSES) was a multi-center study evaluating whether short-term controlled exposure of older, healthy individuals to low levels of ozone (O<sub>3</sub>) induced acute changes in cardiovascular biomarkers. In MOSES Part 1 (MOSES 1), controlled O<sub>3</sub> exposure caused concentration-related reductions in lung function with evidence of airway inflammation and injury, but without convincing evidence of effects on cardiovascular f  ...[more]

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