Predictors of progression from moderate to severe coronavirus disease 2019: a retrospective cohort.

ABSTRACT:

Objective

Most cases of coronavirus disease 2019 (COVID-19) are identified as moderate, which is defined as having a fever or dry cough and lung imaging with ground-glass opacities. The risk factors and predictors of prognosis in such cohorts remain uncertain.

Methods

All adults with COVID-19 of moderate severity diagnosed using quantitative RT-PCR and hospitalized at the Central Hospital of Wuhan, China, from 1 January to 20 March 2020 were enrolled in this retrospective study. The main outcomes were progression from moderate to severe or critical condition or death.

Results

Among the 456 enrolled patients with moderate COVID-19, 251/456 (55.0%) had poor prognosis. Multivariate logistic regression analysis identified higher neutrophil count: lymphocyte count ratio (N

SUBMITTER: Cheng B 

PROVIDER: S-EPMC7331556 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature