A marine photosynthetic microbial cell factory as a platform for spider silk production.

ABSTRACT: Photosynthetic microorganisms such as cyanobacteria, purple bacteria and microalgae have attracted great interest as promising platforms for economical and sustainable production of bioenergy, biochemicals, and biopolymers. Here, we demonstrate heterotrophic production of spider dragline silk proteins, major ampullate spidroins (MaSp), in a marine photosynthetic purple bacterium, Rhodovulum sulfidophilum, under both photoheterotrophic and photoautotrophic growth conditions. Spider silk is a biodegradable and biocompatible material with remarkable mechanical properties. R. sulfidophilum grow by utilizing abundant and renewable nonfood bioresources such as seawater, sunlight, and gaseous CO₂ and N₂, thus making this photosynthetic microbial cell factory a promising gree

SUBMITTER: Foong CP 

PROVIDER: S-EPMC7343832 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature