Ontology highlight
ABSTRACT:
SUBMITTER: Mengel-From J
PROVIDER: S-EPMC7357451 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Mengel-From Jonas J Svane Anne Marie AM Pertoldi Cino C Nygaard Kristensen Torsten T Loeschcke Volker V Skytthe Axel A Christensen Kaare K Lindahl-Jacobsen Rune R Hjelmborg Jacob J Christiansen Lene L
The journals of gerontology. Series A, Biological sciences and medical sciences 20191101 12
Aging is a multifactorial trait caused by early as well as late-life circumstances. A society trend that parents deliberately delay having children is of concern to health professionals, for example as advanced parental age at conception increases disease risk profiles in offspring. We here aim to study if advanced parental age at conception affects mitochondrial DNA content, a cross-species biomarker of general health, in adult human twin offspring and in a model organism. We find no deteriorat ...[more]