Infectious Etiologies of Intussusception Among Children <2 Years Old in 4 Asian Countries.

ABSTRACT:

Background

The etiology of intussusception, the leading cause of bowel obstruction in infants, is unknown in most cases. Adenovirus has been associated with intussusception and slightly increased risk of intussusception with rotavirus vaccination has been found. We conducted a case-control study among children <2 years old in Bangladesh, Nepal, Pakistan, and Vietnam to evaluate infectious etiologies of intussusception before rotavirus vaccine introduction.

Methods

From 2015 to 2017, we enrolled 1-to-1 matched intussusception cases and hospital controls; 249 pairs were included. Stool specimens were tested for 37 infectious agents using TaqMan Array technology. We used conditional logistic regression to estimate odds ratio (OR) and 95% confidence interval (CI) of each pathoge

SUBMITTER: Burnett E 

PROVIDER: S-EPMC7371463 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature