Phthalate and Bisphenol Exposure during Pregnancy and Offspring Nonverbal IQ.

ABSTRACT:

Background

Prenatal exposures to phthalates and bisphenols are associated with impaired brain development in animals. However, epidemiological studies investigating the association between prenatal phthalate or bisphenol exposure and cognition have produced mixed findings and mostly had modest sample sizes and measured the exposure during the third trimester.

Objective

We examined the association between pregnancy maternal urinary biomarkers of phthalate or bisphenol exposure and nonverbal intelligence quotient (IQ) in children 6 years of age.

Method

The study sample consisted of 1,282 mother-child pairs participating in the Generation R Study, a population-based birth cohort in Rotterdam, Netherlands (enrollment 2002-2006). We measured maternal urinary concentrations

SUBMITTER: van den Dries MA 

PROVIDER: S-EPMC7384796 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature