Ontology highlight
ABSTRACT:
SUBMITTER: Poulos RC
PROVIDER: S-EPMC7393074 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Nature communications 20200730 1
Reproducible research is the bedrock of experimental science. To enable the deployment of large-scale proteomics, we assess the reproducibility of mass spectrometry (MS) over time and across instruments and develop computational methods for improving quantitative accuracy. We perform 1560 data independent acquisition (DIA)-MS runs of eight samples containing known proportions of ovarian and prostate cancer tissue and yeast, or control HEK293T cells. Replicates are run on six mass spectrometers o ...[more]