Weight Change 2 Years After Termination of the Intensive Lifestyle Intervention in the Look AHEAD Study.

ABSTRACT: OBJECTIVE:This study evaluated weight changes after cessation of the 10-year intensive lifestyle intervention (ILI) in the Look AHEAD (Action for Health in Diabetes) study. It was hypothesized that ILI participants would be more likely to gain weight during the 2-year observational period following termination of weight-loss-maintenance counseling than would participants in the diabetes support and education (DSE) control group. METHODS:Look AHEAD was a randomized controlled trial that compared the effects of ILI and DSE on cardiovascular morbidity and mortality in participants with overweight/obesity and type 2 diabetes. Look AHEAD was converted to an observational study in September 2012. RESULTS:Two years after the end of the intervention (EOI), ILI and DSE participants lost a mean? (SE) of 1.2 ?(0.2) kg and 1.8? (0.2) kg, respectively (P?=?0.003). In addition, 31% of ILI and 23.9% of DSE participants gained???2% (P?

SUBMITTER: Look AHEAD Research Group 

PROVIDER: S-EPMC7437140 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature