The impact of order with radiation therapy in stage IIIA pathologic N2 NSCLC patients: a population-based study.

ABSTRACT:

Background

The aim of this study was to investigate the optimal order of radiation therapy in patients affected by stage IIIA pathologic N2 (IIIA/N2) non-small-cell lung cancer (NSCLC) and to identify its potential risk factors.

Methods

17,654 (8786 men and 8868 women) diagnosed with NSCLC stage IIIA-N2 from 2004 to 2015 patients were identified in the Surveillance, Epidemiology, and End Results (SEER) database. Among the relevant clinical parameters, we evaluated overall survival (OS), lung cancer-specific survival (LCSS) and other variables such as age, sex and tumor size in patients who were treated with different combinations of surgery and radiotherapy strategies.

Results

We discovered that surgery benefit in younger IIIA/N2 NSCLC patients (age ≤ 75), and compare

SUBMITTER: Duan H 

PROVIDER: S-EPMC7448510 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature