Reducing C. difficile in children: An agent-based modeling approach to evaluate intervention effectiveness.

ABSTRACT:

Objective

Clostridioides difficile infection (CDI) is rapidly increasing in children's hospitals nationwide. Thus, we aimed to compare the effectiveness of 9 infection prevention interventions and 6 multiple-intervention bundles at reducing hospital-onset CDI and asymptomatic C. difficile colonization.

Design

Agent-based simulation model of C. difficile transmission.

Setting

Computer-simulated, 80-bed freestanding, tertiary-care pediatric hospital, including 8 identical wards with 10 single-bed patient rooms each.

Participants

The model includes 5 distinct agent types: patients, visitors, caregivers, nurses, and physicians.

Interventions

Daily and terminal environmental disinfection, screening at admission, reduced intrahospital patient transfers, health

SUBMITTER: Barker AK 

PROVIDER: S-EPMC7461244 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature