Ontology highlight
ABSTRACT:
SUBMITTER: Mlcochova P
PROVIDER: S-EPMC7462534 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Mlcochova Petra P Collier Dami D Ritchie Allyson A Assennato Sonny M SM Hosmillo Myra M Goel Neha N Meng Bo B Chatterjee Krishna K Mendoza Vivien V Temperton Nigel N Kiss Leo L James Leo C LC Ciazynska Katarzyna A KA Xiong Xiaoli X Briggs John A G JAG Nathan James A JA Mescia Federica F Bergamaschi Laura L Zhang Hongyi H Barmpounakis Petros P Demeris Nikos N Skells Richard R Lyons Paul A PA Bradley John J Baker Steven S Allain Jean Pierre JP Smith Kenneth G C KGC Bousfield Rachel R Wilson Michael M Sparkes Dominic D Amoroso Glenn G Gkrania-Klotsas Effrosyni E Hardwick Susie S Boyle Adrian A Goodfellow Ian I Gupta Ravindra K RK
Cell reports. Medicine 20200901 6
Rapid COVID-19 diagnosis in the hospital is essential, although this is complicated by 30%-50% of nose/throat swabs being negative by SARS-CoV-2 nucleic acid amplification testing (NAAT). Furthermore, the D614G spike mutant dominates the pandemic and it is unclear how serological tests designed to detect anti-spike antibodies perform against this variant. We assess the diagnostic accuracy of combined rapid antibody point of care (POC) and nucleic acid assays for suspected COVID-19 disease due to ...[more]