Autologous platelet-rich plasma in the treatment of refractory corneal ulcers: A case report.
Ontology highlight
ABSTRACT: Purpose
To evaluate the efficacy of a low-cost preparation of platelet-rich plasma (PRP) eye drops in the treatment of persistent non-infectious corneal ulcer.Observations
A 67-year-old female presented to our clinic with a wide corneal ulcer and severe paracentral corneal thinning refractory to medical therapy with antibiotics, lubricant and contact lens bandage. The patient received a novel preparation of PRP solution. After 15 days of therapy, we observed complete resolution of the corneal ulcer with regrowth of the epithelium and a reduction in corneal opacity.Conclusion and importance
Although the low-cost PRP preparation gives a lower platelet concentration than standard procedures, our work shows this preparation to be effective in the treatment of refractory non-infectious corneal ulcer.
SUBMITTER: Rechichi M
PROVIDER: S-EPMC7472805 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Publications
Autologous platelet-rich plasma in the treatment of refractory corneal ulcers: A case report.
Rechichi Miguel M Ferrise Marco M Romano Francesco F Gallelli Luca L Toschi Vincenzo V Dominijanni Andrea A Meduri Alessandro A
American journal of ophthalmology case reports 20200821
<h4>Purpose</h4>To evaluate the efficacy of a low-cost preparation of platelet-rich plasma (PRP) eye drops in the treatment of persistent non-infectious corneal ulcer.<h4>Observations</h4>A 67-year-old female presented to our clinic with a wide corneal ulcer and severe paracentral corneal thinning refractory to medical therapy with antibiotics, lubricant and contact lens bandage. The patient received a novel preparation of PRP solution. After 15 days of therapy, we observed complete resolution o ...[more]
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