An approach to classifying subjective cognitive decline in community-dwelling elders.

ABSTRACT:

Introduction

Subjective cognitive decline (SCD) may be an early symptomatic manifestation of Alzheimer's disease, though published research largely neglects how to classify SCD in community-based studies.

Methods

In neuropsychologically intact Einstein Aging Study participants (n = 1115; mean age = 78; 63% female; 30% non-White), we used Cox models to examine the association between self-perceived cognitive functioning at baseline (using three different approaches) and incident amnestic mild cognitive impairment (aMCI) with covariates of age, sex, education, race/ethnicity, general (objective) cognition, depressive symptoms, and four other SCD-related features.

Results

After a median of 3 years, 198 participants developed aMCI. In models that included all the variable

SUBMITTER: Rabin LA 

PROVIDER: S-EPMC7521594 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature