Thrombolysis implementation intervention and clinical outcome: a secondary analysis of a cluster randomized trial.

ABSTRACT:

Background

Multiple studies have attempted to increase the rate of intravenous thrombolysis for ischemic stroke using interventions to promote adherence to guidelines. Still, many of them did not measure individual-level impact. This study aimed to make a posthoc comparison of the clinical outcomes of patients in the "Thrombolysis ImPlementation in Stroke (TIPS)" study, which aimed to improve rates of intravenous thrombolysis in Australia.

Methods

A posthoc analysis was conducted using individual-level patient data. Excellent (Three-month post treatment modified Rankin Score 0-2) and poor clinical outcome (Three-month post treatment modified Rankin Score 5-6) and post treatment parenchymal haematoma were the three main outcomes, and a mixed logistic regression model was used

SUBMITTER: Hasnain MG 

PROVIDER: S-EPMC7542125 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature