Stereoselective α-Tertiary Alkylation of N-(Arylacetyl)oxazolidinones.

ABSTRACT: A method has been developed for the α-tertiary alkylation of zirconium enolates of N-(arylacetyl)oxazolidinones. This reaction directly installs an all-carbon quaternary center vicinal to a benzylic tertiary carbon in a highly diastereoselective manner.

SUBMITTER: Shim E 

PROVIDER: S-EPMC7544157 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature