Relationship between serum B12 concentrations and mortality: experience in NHANES.

ABSTRACT:

Background

There is conflicting evidence in the literature on the association between (elevated) serum B12 concentrations and subsequent disease or mortality. We evaluated in the NHANES general population the association of serum B12 concentrations as well as vitamin B12 supplement intake with all-cause, cardiovascular, and cancer-related mortality, while taking into account demographic and lifestyle factors and significant other diseases which are known to be associated with poorer outcome.

Methods

The main outcomes of our study were all-cause mortality, cardiovascular mortality, and cancer-related mortality. Mortality status and cause of death were determined by NHANES-linked National Death Index public access files through December 31, 2015. The association of serum B12 c

SUBMITTER: Wolffenbuttel BHR 

PROVIDER: S-EPMC7545540 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature