TRic: a user-friendly data portal to explore the expression landscape of tRNAs in human cancers.
Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Z
PROVIDER: S-EPMC7567503 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Publications
tRic: a user-friendly data portal to explore the expression landscape of tRNAs in human cancers.
Zhang Zhao Z Ruan Hang H Liu Chun-Jie CJ Ye Youqiong Y Gong Jing J Diao Lixia L Guo An-Yuan AY Han Leng L
RNA biology 20190825 11
Transfer RNAs (tRNAs) play critical roles in human cancer. Currently, no database provides the expression landscape and clinical relevance of tRNAs across a variety of human cancers. Utilizing miRNA-seq data from The Cancer Genome Atlas, we quantified the relative expression of tRNA genes and merged them into the codon level and amino level across 31 cancer types. The expression of tRNAs is associated with clinical features of patient smoking history and overall survival, and disease stage, subt ...[more]
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