Adjusting antimullerian hormone levels for age and body mass index improves detection of polycystic ovary syndrome.

ABSTRACT:

Objective

To examine whether accounting for a woman's age and body mass index (BMI) would improve the ability of antimüllerian hormone (AMH) to distinguish between women with (cases) and without (controls) polycystic ovarian syndrome (PCOS).

Design

An opportunistic case-control dataset of reproductive age women having evaluations for PCOS as defined by National Institutes of Health criteria.

Setting

Two medical centers in the United States enrolled women. Serum samples were analyzed for relevant analytes.

Patients

Women were between 18 and 39 years of age when samples and clinical information were collected. Residual samples had been stored for 2-17 years. AMH was measured via immunoassay.

Interventions

None; this was an observational study.

Main outc

SUBMITTER: Palomaki GE 

PROVIDER: S-EPMC7583345 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature