Analysis of the strategy of LT4 prescribing and TSH monitoring for thyroid carcinoma after lobectomy.

ABSTRACT:

Background

Thyrotropin (TSH) suppression is a critical step in the management of differentiated thyroid carcinoma (DTC). The objectives of this study were to evaluate changes in TSH levels and a strategy of initial levothyroxine (LT4) supplementation for TSH suppression in low-risk differentiated thyroid carcinoma (lr-DTC) patients after lobectomy.

Methods

One hundred and ten patients with lr-DTC who received lobectomy were enrolled. Each of the patients was given 50 µg LT4 immediately after lobectomy and were retrospectively analyzed to evaluate the initial dose of LT4 suppression during the first year of follow-up. Risk factors influencing the TSH trend were also evaluated.

Results

Median TSH levels decreased significantly after lobectomy and the initiation of LT4 s

SUBMITTER: Wang Z 

PROVIDER: S-EPMC7607107 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature