Effects of radioactive iodine treatment on cardiovascular disease in thyroid cancer patients: a nationwide cohort study.

ABSTRACT:

Background

Radioactive iodine (RAI) treatment is a standard treatment in differentiated thyroid cancer (TC). However, its adverse effects on cardiovascular diseases (CVDs) have not been clearly elucidated.

Methods

In this retrospective cohort study based on the Korean National Health Insurance Service-National Health Screening Cohort (2002-2015), we analyzed 4,845 patients with TC with a median follow-up of 66 months. We evaluated and compared the risk of CVD between patients treated with and without RAI therapy. The primary CVD outcome was defined as a composite of ischemic stroke (IS), ischemic heart disease (IHD), hemorrhagic stroke (HS), or heart failure (HF).

Results

Overall, 2,533 patients (52.3%) received RAI treatment with a median cumulative dosage of 103 mCi

SUBMITTER: Kim KJ 

PROVIDER: S-EPMC7607121 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature