The conundrum of asymptomatic carotid stenosis-determinants of decision and evidence.

ABSTRACT: Management of asymptomatic carotid disease continues to challenge medical practice and present evidence is often conflicting. Stroke is a significant burden in Public Health and 11% to 15% appear as first neurologic event associated with asymptomatic carotid stenosis. Randomized trials provided support for Guidelines and Recommendations to intervene on asymptomatic stenosis, but at a known cost of a high number of unnecessary operations. Conflicting evidence from natural history studies and the widespread use of proper medical management including risk factors control, lowering-lipid drugs and strict control of arterial hypertension have reduced the incidence of strokes associated to asymptomatic carotid disease challenging established practice. Need to identify vulnerable lesions prone to

SUBMITTER: Fernandes E Fernandes J 

PROVIDER: S-EPMC7607137 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature