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RELEASE: a protocol for a systematic review based, individual participant data, meta- and network meta-analysis, of complex speech-language therapy interventions for stroke-related aphasia.


ABSTRACT:

Background

Speech and language therapy (SLT) benefits people with aphasia following stroke. Group level summary statistics from randomised controlled trials hinder exploration of highly complex SLT interventions and a clinically relevant heterogeneous population. Creating a database of individual participant data (IPD) for people with aphasia aims to allow exploration of individual and therapy-related predictors of recovery and prognosis.

Aim

To explore the contribution that individual participant characteristics (including stroke and aphasia profiles) and SLT intervention components make to language recovery following stroke.

Methods and procedures

We will identify eligible IPD datasets (including randomised controlled trials, non-randomised comparison studies, obser

SUBMITTER: Brady MC 

PROVIDER: S-EPMC7614912 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

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