Project description:We demonstrate that the Cdc7/Dbf4-dependent histone modification, H3 threonine 45 phosphorylation (H3T45p), is specifically enriched at origins of replication, and highly transcribed genes involved in protein synthesis and glycolysis. Furthermore, we show that H3T45p also mediates polymerase recruitment and expression of these genes.

2022-01-09 | GSE43737 | GEO

A DNMT3A PWWP mutation leads to methylation of bivalent chromatin and growth retardation in mice.

Project description: Not available

| S-EPMC6478690 | biostudies-literature

Structure-specific recognition protein-1 (SSRP1) is an elongated homodimer that binds histones.

Project description: Not available

| S-EPMC6028955 | biostudies-literature

Xist RNA binds select autosomal genes and depends on Repeat B to regulate their expression.

Project description: Not available

| S-EPMC11291044 | biostudies-literature

RLF and ZFP292 regulate bivalent genes through CoREST complex [RNA-seq]

Project description:This dataset includes ChIP-seq and RNA-seq data derived from mouse embryonic stem cells (mESCs) to investigate the roles of RLF and ZFP292 in transcriptional regulation and chromatin organization.

2026-03-17 | GSE297950 | GEO

RLF and ZFP292 regulate bivalent genes through CoREST complex [ChIP-seq]

2026-03-17 | GSE297949 | GEO

Inhalation of an RNA aptamer that selectively binds extracellular histones protects from acute lung injury.

Project description: Not available

| S-EPMC9999168 | biostudies-literature

Dengue virus capsid protein binds core histones and inhibits nucleosome formation in human liver cells.

Project description: Not available

| S-EPMC3164731 | biostudies-literature