Dataset Information
Safety of age-dosed, single low-dose primaquine in children with glucose-6-phosphate dehydrogenase deficiency who are infected with Plasmodium falciparum in Uganda and the Democratic Republic of the Congo: a randomised, double-blind, placebo-controlled, non-inferiority trial.
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ABSTRACT:
SUBMITTER: Taylor WR
PROVIDER: S-EPMC7618244 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature
Publications
Safety of age-dosed, single low-dose primaquine in children with glucose-6-phosphate dehydrogenase deficiency who are infected with Plasmodium falciparum in Uganda and the Democratic Republic of the Congo: a randomised, double-blind, placebo-controlled, non-inferiority trial.
The Lancet. Infectious diseases 20221130 4
<h4>Background</h4>WHO recommends gametocytocidal, single low-dose primaquine for blocking the transmission of Plasmodium falciparum; however, safety concerns have hampered the implementation of this strategy in sub-Saharan Africa. We aimed to investigate the safety of age-dosed, single low-dose primaquine in children from Uganda and the Democratic Republic of the Congo.<h4>Methods</h4>We conducted this randomised, double-blind, placebo-controlled, non-inferiority trial at the Mbale Regional Ref ...[more]
