Is older age associated with COVID-19 mortality in the absence of other risk factors? General population cohort study of 470,034 participants.

ABSTRACT:

Introduction

Older people have been reported to be at higher risk of COVID-19 mortality. This study explored the factors mediating this association and whether older age was associated with increased mortality risk in the absence of other risk factors.

Methods

In UK Biobank, a population cohort study, baseline data were linked to COVID-19 deaths. Poisson regression was used to study the association between current age and COVID-19 mortality.

Results

Among eligible participants, 438 (0.09%) died of COVID-19. Current age was associated exponentially with COVID-19 mortality. Overall, participants aged ≥75 years were at 13-fold (95% CI 9.13-17.85) mortality risk compared with those <65 years. Low forced expiratory volume in 1 second, high systolic blood pressure, low hand

SUBMITTER: Ho FK 

PROVIDER: S-EPMC7644030 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature