Loneliness Relates to Functional Mobility in Older Adults with Type 2 Diabetes: The Look AHEAD Study.
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ABSTRACT: Objective
Little is known about the impact of loneliness on physical health among elderly individuals with diabetes. Here, we examined the relationship of loneliness with disability, objective physical function, and other health outcomes in older individuals with type 2 diabetes and overweight or obesity.Method
Data are drawn from the Look AHEAD study, a diverse cohort of individuals (ages 61-92) with overweight or obesity and type 2 diabetes measured 5-6 years after a 10-year weight loss randomized, controlled trial.Results
Loneliness scores were significantly associated with greater disability symptoms and slower 4-meter gait speed (ps < 0.01). Loneliness did not differ across treatment arms. Discussion. Overall, these results extend prior findings relating loneliness to disability and decreased mobility to older individuals with type 2 diabetes and overweight or obesity.
SUBMITTER: McCaffery JM
PROVIDER: S-EPMC7647748 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Loneliness Relates to Functional Mobility in Older Adults with Type 2 Diabetes: The Look AHEAD Study.
McCaffery Jeanne M JM Anderson Andrea A Coday Mace M Espeland Mark A MA Gorin Amy A AA Johnson Karen C KC Knowler William C WC Myers Candice A CA Rejeski W Jack WJ Steinberg Helmut O HO Steptoe Andrew A Wing Rena R RR
Journal of aging research 20201030
<h4>Objective</h4>Little is known about the impact of loneliness on physical health among elderly individuals with diabetes. Here, we examined the relationship of loneliness with disability, objective physical function, and other health outcomes in older individuals with type 2 diabetes and overweight or obesity.<h4>Method</h4>Data are drawn from the Look AHEAD study, a diverse cohort of individuals (ages 61-92) with overweight or obesity and type 2 diabetes measured 5-6 years after a 10-year we ...[more]
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Project description:BackgroundLifestyle interventions have been shown to improve physical function over the short term; however, whether these benefits are sustainable is unknown. The long-term effects of an intensive lifestyle intervention (ILI) on physical function were assessed using a randomized post-test design in the Look AHEAD trial.MethodsOverweight and obese (body mass index ≥ 25 kg/m2) middle-aged and older adults (aged 45-76 years at enrollment) with type 2 diabetes enrolled in Look AHEAD, a trial evaluating an ILI designed to achieve weight loss through caloric restriction and increased physical activity compared to diabetes support and education (DSE), underwent standardized assessments of performance-based physical function including a 4- and 400-m walk, lower extremity physical performance (expanded Short Physical Performance Battery, SPPBexp), and grip strength approximately 11 years postrandomization and 1.5 years after the intervention was stopped (n = 3,783).ResultsIndividuals randomized to ILI had lower odds of slow gait speed (<0.8 m/s) compared to those randomized to DSE (adjusted OR [95% CI]: 0.84 [0.71 to 0.99]). Individuals randomized to ILI also had faster gait speed over 4- and 400-m (adjusted mean difference [95% CI]: 0.019 [0.007 to 0.031] m/s, p = .002, and 0.023 [0.012 to 0.034] m/sec, p < .0001, respectively) and higher SPPBexp scores (0.037 [0.011 to 0.063], p = .005) compared to those randomized to DSE. The intervention effect was slightly larger for SPPBexp scores among older versus younger participants (0.081 [0.038 to 0.124] vs 0.013 [-0.021 to 0.047], p = .01).ConclusionsAn intensive lifestyle intervention has modest but significant long-term benefits on physical function in overweight and obese middle-aged and older adults with type 2 diabetes.Clinicaltrials.gov identifierNCT00017953.
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