Assessment of serological techniques for screening patients for COVID-19 (COVID-SER): a prospective, multicentric study.

ABSTRACT:

Introduction

The COVID-19 pandemic caused by SARS-CoV-2 threatens global public health, and there is an urgent public health need to assess acquired immunity to SARS-CoV-2. Serological tests might provide results that can be complementary to or confirm suspected COVID-19 cases and reveal previous infection. The performance of serological assays (sensitivity and specificity) has to be evaluated before their use in the general population. The neutralisation capacity of the produced antibodies also has to be evaluated.

Methods and analysis

We set up a prospective, multicentric clinical study to evaluate the performance of serological kits among a population of healthcare workers presenting mild symptoms suggestive of SARS-CoV-2 infection. Four hundred symptomatic healthcare wor

SUBMITTER: Trouillet-Assant S 

PROVIDER: S-EPMC7688438 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature