Medication adherence/persistence among patients with active multiple sclerosis in Finland.

ABSTRACT:

Objectives

To explore adherence, persistence, and treatment patterns in patients with multiple sclerosis (MS) in Finland treated with disease-modifying therapies (DMTs) for active MS in 2005-2018.

Materials and methods

The study cohort was identified using the Drug Prescription Register of Social Insurance Institute, Finland. All patients had at least one prescription of glatiramer acetate (GA), beta-interferons, teriflunomide, or delayed-release dimethyl fumarate (DMF). Adherence was calculated using proportion of days covered (PDC) (cutoff ≥0.8). Time to non-persistence was calculated by the number of days on index DMT treatment before the first treatment gap (≥90 days) or switch and analyzed with time-to-event methodology.

Results

The cohort included 7474 MS patien

SUBMITTER: Lahdenpera S 

PROVIDER: S-EPMC7689851 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature