Left ventricular remodeling and dysfunction in obstructive sleep apnea : Systematic review and meta-analysis.

ABSTRACT:

Background

Obstructive sleep apnea syndrome (OSAS) is associated with cardiovascular mortality and morbidity. Several studies have reported that it affects the left ventricle; however, large randomized controlled trials are lacking. The current study aimed to summarize the association between OSAS and left ventricular (LV) structure and function.

Methods

Electronic databases (PubMed, Embase, and Cochrane) and references were searched for articles published until March 2018. A systematic review and meta-analysis were performed to assess LV structure and function in OSAS patients based on echocardiography.

Results

In total, 17 studies with 747 OSAS patients and 426 control participants were included. Patients with OSAS showed an increase in LV diastolic diameter (weight

SUBMITTER: Yu L 

PROVIDER: S-EPMC7695673 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature