The prognostic value of Presepsin for postoperative complications following pancreatic resection: A prospective study.

ABSTRACT:

Background

Presepsin is involved in binding lipopolysaccharides and previous studies have confirmed its value as a marker for early diagnosis and prediction of severity in sepsis. Comparable studies assessing the predictive potential regarding postoperative complications and mortality following pancreatic resection are lacking.

Methods

This prospective study included 70 patients undergoing pancreatic resection from December 2017 until May 2019. Presepsin was measured preoperatively, on postoperative day 1, 3 and 8 (POD1/3/8) and correlated with the clinical course and mortality.

Results

Severe complications (Clavien-Dindo ≥3a) occurred in 28 patients (40%), postoperative pancreatic fistula (POPF) grade B/C occurred in 20 patients (28.6%), infectious complications in 2

SUBMITTER: Gasteiger S 

PROVIDER: S-EPMC7725319 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature