Ontology highlight
ABSTRACT:
SUBMITTER: Prasad S
PROVIDER: S-EPMC7758333 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Communications biology 20201223 1
The stereocilia of the inner ear sensory cells contain the actin-binding protein radixin, encoded by RDX. Radixin is important for hearing but remains functionally obscure. To determine how radixin influences hearing sensitivity, we used a custom rapid imaging technique to visualize stereocilia motion while measuring electrical potential amplitudes during acoustic stimulation. Radixin inhibition decreased sound-evoked electrical potentials. Other functional measures, including electrically induc ...[more]